Single Service

Polynucleotides – Per Session

Unlock the power of cellular restoration with Bio-Regenerative Therapy at Rose Hill Aesthetics. Unlike traditional fillers that merely provide volume, Polynucleotides (PN) are highly purified DNA fractions that act as biological signals to “reboot” your skin’s natural repair mechanisms. By stimulating fibroblast activity and increasing tissue hydration at a molecular level, this treatment fundamentally restores skin elasticity, improves texture, and repairs damage in delicate areas—most notably the periorbital (under-eye) region—where other treatments may fall short.

Benefits of Polynucleotides – Per Session

Targeted Tissue Repair: Exceptional for revitalizing the under-eye area, reducing dark circles, and smoothing fine “crepey” skin that is resistant to other therapies.

Deep Molecular Hydration: PN chains attract and bind water molecules, resulting in long-term, internal hydration that significantly improves skin density and glow.

Scar & Texture Refinement: Effectively smooths surgical or acne scarring and refines overall skin texture by promoting a more organized dermal matrix.

Polynucleotides | Rose Hill Aesthetics

ROSE HILL

Bio-Regenerative Cellular DNA Repair

Polynucleotides

Unlock the power of cellular restoration with Bio-Regenerative Therapy at Rose Hill Aesthetics. Unlike traditional fillers that simply add volume, Polynucleotides (PN) are highly purified DNA fractions that act as biological messengers to "reboot" your skin’s natural repair cycle. By stimulating fibroblast activity and molecular hydration, this treatment fundamentally restores skin density and improves texture, making it the gold standard for delicate areas like the under-eyes.

Key Clinical Points

  • DNA-Fraction Signaling Triggers natural regenerative pathways to significantly increase collagen and elastin production.
  • Molecular Hydration Matrix Attracts water molecules at a cellular level for long-term, internal tissue plumpness.
  • Trophic Dermal Support Provides essential building blocks for cellular repair, improving skin thickness and resilience.
Regenerative Medicine
£250

Per Clinical Session

Under-Eye Specialist

Highly effective for dark circles and crepey periorbital tissue

Oxidative Shield

Potent antioxidant properties that neutralize free radical damage

Bio-Regeneration Process | Rose Hill Aesthetics
Bio-Regenerative Protocol

DNA Restoration

An advanced cellular protocol utilizing DNA fractions to systematically repair and thicken the dermal architecture at Rose Hill Aesthetics.

01

Tissue Integrity Assessment

We begin with a microscopic analysis of skin density and elasticity, particularly around high-fatigue areas like the under-eyes. This allows us to determine the precise volume of Polynucleotide fractions required to trigger meaningful cellular repair.

02

Micro-Dermal Infusion

Utilizing pharmaceutical-grade Polynucleotides, we perform a series of micro-injections into the deep dermis. These DNA fragments act as biostimulators, signaling your skin cells to begin an intensive phase of renewal and collagen synthesis.

03

Fibroblast Signaling

Over the following days, the PN chains stimulate fibroblasts to produce new Type I collagen and elastin. This biological response thickens the skin from within, systematically improving texture and reducing the transparency of thinning tissue.

04

Structural Maturation

Peak results are realized as the new dermal matrix matures. The skin appears more resilient, hydrated, and significantly denser. While some radiance is immediate, the true structural lift develops over 2–4 weeks as cellular repair reaches completion.

Polynucleotides Protocol | Rose Hill Aesthetics

Bio-Regenerative Guidelines

Ensuring Cellular DNA Integration

Allergy & Contraindications:

As Polynucleotides are derived from highly purified salmon DNA, this treatment is strictly contraindicated for individuals with a known severe fish or seafood allergy. Please confirm your status during the clinical screening.

Vascular Management:

To minimize the risk of micro-bruising at the injection sites, avoid alcohol and blood-thinning agents (Ibuprofen, Aspirin) for 48 hours. Discontinue supplements such as Fish Oil or Vitamin E for 7 days prior.

Tissue Hydration Foundation:

Ensure you are well-hydrated leading up to your session. Polynucleotides work by attracting water to the area to stimulate fibroblast activity; high localized hydration levels significantly support the immediate integration of the DNA fractions.

Dermal Stability:

Discontinue the use of high-strength Retinoids and exfoliating acids (AHA/BHA) for 3 days before your session. Ensure the target area is free of active acne, cold sores, or inflammatory skin conditions to maintain a sterile field.

Immediate Dermal Response:

You may notice small "papules" or bumps at the injection sites immediately following treatment. These represent the DNA product beginning its work. Do not massage or attempt to flatten these; they typically resolve naturally within 24–48 hours.

The 12-Hour Sterile Window:

Do not wash the treated area or apply makeup for at least 12 hours. Avoid touching your face to prevent the introduction of bacteria into the micro-injection points. Use a clean, fresh silk pillowcase on the night of your treatment.

Metabolic & Thermal Rest:

Refrain from strenuous cardiovascular exercise, saunas, steam rooms, and hot tubs for 48 hours. Increased body temperature can lead to localized swelling and may interfere with the initial cellular signaling phase of the PN fractions.

Regenerative Protection:

While some radiance is immediate, the true structural lift develops over 2–4 weeks. Protect your investment with SPF 50 daily to ensure UV rays do not degrade the new collagen and elastin fibers being synthesized in the dermis.

Frequently Asked Questions​

How do Polynucleotides differ from Dermal Fillers?
While fillers use Hyaluronic Acid to physically "fill" space and add volume, Polynucleotides are DNA fractions that signal your cells to repair themselves. They improve the actual quality, thickness, and health of the skin tissue rather than just masking a hollow area.
Why is this treatment recommended for the under-eye area?
The periorbital (eye) area has very thin skin. Traditional fillers can sometimes look heavy or cause "puffiness" (Tyndall effect) here. Polynucleotides are ideal because they thicken the dermis and improve dark circles by repairing the skin structure from within.
What are the visible bumps (papules) after treatment?
Because Polynucleotides are delivered into the dermis, you will see small, raised blebs at the injection sites. This is a normal part of the clinical protocol. These reservoirs of DNA fractions are absorbed by your cells typically within 24 to 48 hours.
How many sessions will I need to see results?
Regeneration is a biological process that takes time. While hydration is visible early on, we recommend a clinical course of 3 sessions, spaced 3–4 weeks apart, to achieve the full structural peak and long-term tissue remodeling.
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